Giachelli Lab
  • Microscope Image

This lab is led by Cecilia Giachelli, the Hunter and Dorothy Simpson Endowed Chair in Bioengineering. The Giachelli lab group is inventing the future of medicine by developing molecular and cellular bioengineering approaches to block ectopic calcification and promote healing, biocompatibility, tissue regeneration and biomineralization. Our research includes mechanistic studies aimed at developing novel therapeutic targets and innovative approaches for treating ectopic calcification in disease, traumatic injury, and medical devices. Another area of focus is biomolecular control of the foreign body reaction, with particular emphasis on the macrophage-mediated inflammatory response to biomaterials. We are also working to identify and apply biomimetic strategies to create biointerfaces for soft and hard tissue regeneration.



The Giachelli Lab is funded by the National Heart, Lung, and Blood Institute