Julien Bloch received the Big Data for Genomics and Neuroscience Grant. In his proposal Julien plans to investigate optogenetic and electrical stimulation-induced cortical network reorganization. By understanding how a network interacts with stimulation to produce the network-wide connectivity change, we will gain insight into neuroplasticity dynamics at the in-vivo neural population level and progress towards stimulation based neurotherapies. Julien proposes to leverage datasets of large-scale recording and stimulation of the sensorimotor area in non-human primates, in parallel with computer simulation of large-scale neural dynamics, to investigate how neural stimulation drives connectivity change across a network.